Syringoma vs Milia

Syringoma & Milia

Syringoma and milia treatment model

Syringoma vs milia: what is the difference?

Syringoma and milia are small bumps that often appear around the eyes and can look alike, but their origin and depth in the skin are different. Syringoma is a benign tumor originating from eccrine sweat glands, located in the lower dermis. Milia are keratin cysts derived from skin keratinocytes, located in the lower epidermis close to the skin surface. Because of this, the two are treated with different methods.

CategorySyringomaMilia
OriginBenign tumor originating from eccrine sweat glandsKeratin cyst derived from skin keratinocytes
DepthLower dermis (deep within the skin)Lower epidermis (close to the skin surface)
Typical lookSmall, flat, skin-colored bumps clustered around the eyesWhite, millet-like tiny bumps just beneath the skin
If treated the wrong wayMay recur if shaved away, as the root is not removedSurrounding tissue may be damaged by forceful extraction
Method at The OtherAgnes radiofrequency: an insulated needle delivers energy only at the needle tip, lesion by lesion. Three sessions at 2–3-month intervals are recommendedA tiny opening is made with a CO2 or Er:YAG laser, then the contents are removed

This is a summary of the information on this page. Which of the two a bump is, and how it should be treated, is decided at diagnosis. For details, please book a consultation.

Category

Syringoma

Milia

Origin

Benign tumor originating from eccrine sweat glands
Keratin cyst derived from skin keratinocytes

Primary Location

Lower dermis (deep within the skin)
Lower epidermis (close to the skin surface)

Treatment Risk

Frequent recurrence if shaved away, as the root is not removed
Surrounding tissue may be damaged by forceful extraction

The Other Solution

Agnes radiofrequency destruction

CO2 / Er:YAG micro-opening and removal

Syringoma and milia lesion guide
Precision diagnosis icon
Based on Histological Analysis:
Precision laser treatment icon
Minimized Downtime
Skin hydration icon
Combination Synergy
Dr. Lee Seung-joo, Medical Director of The Other Dermatology Clinic

Is milia the same as syringoma?

No. They can look alike around the eyes, but syringoma is a benign tumor originating from eccrine sweat glands in the lower dermis, while milia are keratin cysts derived from skin keratinocytes in the lower epidermis, close to the skin surface. Because their cause and depth differ, they are treated with different methods.

How can you tell syringoma and milia apart?

Syringomas usually appear as small, flat, skin-colored bumps clustered around the eyes, and they may come back after being removed with laser. Milia look like white, millet-like tiny bumps trapped just beneath the skin. Because the two can look similar, The Other confirms which one it is through histological differential diagnosis before choosing a treatment.

Why do syringomas come back after laser removal?

The main lesion of syringoma is located deep in the dermis. Shaving the surface with conventional CO2 or Er:YAG lasers may only damage normal skin while the deeper tumor remains, which can lead to recurrence. At The Other, a specially insulated Agnes needle delivers radiofrequency energy only to the needle tip where the tumor is located, and each lesion is treated individually.

How are syringoma and milia treated?

Syringoma is treated with Agnes radiofrequency destruction, one lesion at a time. Considering the time needed for tissue destruction and absorption, three sessions at 2–3-month intervals are recommended. Milia are removed by making a very tiny opening at the entrance of the keratin cyst with a CO2 or Er:YAG laser and removing only the contents, without applying excessive force to the surrounding tissue. The right approach for you is decided at consultation.

Should I try to remove milia or syringomas at home?

Forceful extraction of milia may damage the surrounding tissue, and trying to squeeze the bumps out can leave wounds and redness around the area. Syringoma is different again: its main lesion is located deep in the dermis, so removing the surface leaves the tumor in place. Because the two look alike, The Other confirms which one it is before choosing a treatment.